{"product_id":"pfi-6-cooh-2768514-05-0","title":"PFI-6-COOH [CAS 2768514-05-0]","description":"\u003csection class=\"qm-product-editorial\"\u003e\n  \u003cstyle\u003e\n    .qm-product-editorial {\n      --qm-navy: #16244a;\n      --qm-deep-blue: #21345f;\n      --qm-blue: #2696bc;\n      --qm-bg: #f4fbff;\n      --qm-bg-alt: #eef8fc;\n      --qm-text: #2f3745;\n      --qm-border: #cfe8f2;\n      font-family: Arial, Helvetica, sans-serif;\n      color: var(--qm-text);\n      line-height: 1.6;\n      margin: 0;\n      padding: 0;\n    }\n\n    .qm-product-editorial * {\n      box-sizing: border-box;\n    }\n\n    .qm-shell {\n      border: 1px solid var(--qm-border);\n      background: #ffffff;\n      padding: 28px;\n      margin: 24px 0;\n    }\n\n    .qm-hero {\n      border-left: 6px solid var(--qm-blue);\n      background: var(--qm-bg);\n      padding: 24px;\n      margin-bottom: 24px;\n    }\n\n    .qm-hero h2 {\n      color: var(--qm-navy);\n      font-size: 28px;\n      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color: var(--qm-deep-blue);\n      font-weight: 700;\n      margin-bottom: 6px !important;\n    }\n\n    .qm-ref-list {\n      padding-left: 20px;\n      margin: 0;\n    }\n\n    .qm-ref-list a {\n      color: var(--qm-blue);\n      text-decoration: underline;\n      font-weight: 700;\n    }\n\n    .qm-disclaimer {\n      border-top: 4px solid var(--qm-blue);\n      background: var(--qm-bg);\n      padding: 16px;\n      color: var(--qm-navy);\n      font-weight: 700;\n      margin-top: 22px;\n      font-size: 16px;\n    }\n\n    @media (max-width: 720px) {\n      .qm-shell {\n        padding: 18px;\n      }\n\n      .qm-hero {\n        padding: 18px;\n      }\n\n      .qm-hero h2 {\n        font-size: 24px;\n      }\n\n      .qm-grid {\n        grid-template-columns: 1fr;\n      }\n    }\n  \u003c\/style\u003e\n\n  \u003cdiv class=\"qm-shell\"\u003e\n    \u003cdiv class=\"qm-hero\"\u003e\n      \u003cdiv class=\"qm-kicker\"\u003eResearch compound for epigenetic reader-domain workflows\u003c\/div\u003e\n      \u003ch2\u003ePFI-6-COOH for ENL ligand and PROTAC synthesis research\u003c\/h2\u003e\n      \u003cp\u003ePFI-6-COOH, CAS 2768514-05-0, is listed by QuantiMol as a research compound associated with epigenetic reader-domain work and ligands for target proteins in PROTAC-related synthesis workflows.\u003c\/p\u003e\n      \u003cp\u003eThis editorial block is designed to complement the product details above, including the listed molecular formula C23H21N3O6, molecular weight 435.43, and SMILES structure.\u003c\/p\u003e\n    \u003c\/div\u003e\n\n    \u003cdiv class=\"qm-grid\"\u003e\n      \u003cdiv class=\"qm-panel\"\u003e\n        \u003ch3\u003eSearch and entity terms\u003c\/h3\u003e\n        \u003cul class=\"qm-tag-list\" aria-label=\"Search terms for PFI-6-COOH\"\u003e\n          \u003cli\u003ePFI-6-COOH\u003c\/li\u003e\n          \u003cli\u003eCAS 2768514-05-0\u003c\/li\u003e\n          \u003cli\u003eCompound 18\u003c\/li\u003e\n          \u003cli\u003eENL ligand\u003c\/li\u003e\n          \u003cli\u003eMLLT1 \/ ENL research\u003c\/li\u003e\n          \u003cli\u003eEpigenetic reader domain\u003c\/li\u003e\n          \u003cli\u003ePROTAC ligand workflow\u003c\/li\u003e\n          \u003cli\u003eMS41 synthesis research\u003c\/li\u003e\n        \u003c\/ul\u003e\n      \u003c\/div\u003e\n\n      \u003cdiv class=\"qm-panel\"\u003e\n        \u003ch3\u003eProduct context\u003c\/h3\u003e\n        \u003cp\u003ePFI-6-COOH is relevant for laboratories working with ENL-related chemical biology, epigenetic reader-domain ligand design, and synthesis planning for PROTAC degrader research.\u003c\/p\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n\n    \u003cdiv class=\"qm-section\"\u003e\n      \u003ch3\u003eHow researchers use this compound\u003c\/h3\u003e\n      \u003cul class=\"qm-list\"\u003e\n        \u003cli\u003eUsed in research workflows involving ENL, also known as eleven-nineteen leukemia protein or MLLT1.\u003c\/li\u003e\n        \u003cli\u003eUsed as a ligand building block in PROTAC-oriented synthesis workflows, including literature-associated work around the ENL degrader MS41.\u003c\/li\u003e\n        \u003cli\u003eRelevant for medicinal chemistry, chemical biology, and epigenetic reader-domain method development.\u003c\/li\u003e\n        \u003cli\u003eSuitable for laboratory teams comparing ENL ligand structures, linker attachment points, and degrader design strategies.\u003c\/li\u003e\n      \u003c\/ul\u003e\n    \u003c\/div\u003e\n\n    \u003cdiv class=\"qm-section\"\u003e\n      \u003ch3\u003eSelection notes for laboratory teams\u003c\/h3\u003e\n      \u003cul class=\"qm-list\"\u003e\n        \u003cli\u003eConfirm that the requested material corresponds to CAS 2768514-05-0 and the listed formula C23H21N3O6.\u003c\/li\u003e\n        \u003cli\u003eUse the visible SMILES string on the product page when aligning the compound with internal registration, informatics, or synthesis records.\u003c\/li\u003e\n        \u003cli\u003eThe QuantiMol page lists room-temperature shipping conditions; no separate verified storage temperature was visible on the checked product page.\u003c\/li\u003e\n        \u003cli\u003eNo visible purity, solubility, or InChIKey value was identified on the checked QuantiMol product page.\u003c\/li\u003e\n      \u003c\/ul\u003e\n    \u003c\/div\u003e\n\n    \u003cdiv class=\"qm-section\"\u003e\n      \u003ch3\u003eSafety and hazard note\u003c\/h3\u003e\n      \u003cdiv class=\"qm-safety\"\u003e\n        \u003cp\u003e\u003cstrong\u003eHazard Statements:\u003c\/strong\u003e No compound-specific GHS hazard statements were found in the checked neutral sources.\u003c\/p\u003e\n        \u003cp\u003e\u003cstrong\u003ePrecautionary Statements:\u003c\/strong\u003e No verified compound-specific precautionary statements were identified in the checked neutral sources.\u003c\/p\u003e\n        \u003cp\u003eHandle as a laboratory research chemical using institutionally appropriate controls for small-molecule research materials.\u003c\/p\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n\n    \u003cdiv class=\"qm-faq\"\u003e\n      \u003ch3\u003eFAQ\u003c\/h3\u003e\n\n      \u003cdiv class=\"qm-faq-item\"\u003e\n        \u003cp class=\"qm-faq-q\"\u003eWhat is PFI-6-COOH used for?\u003c\/p\u003e\n        \u003cp\u003ePFI-6-COOH is used in research workflows involving ENL ligand chemistry and PROTAC-related synthesis planning.\u003c\/p\u003e\n      \u003c\/div\u003e\n\n      \u003cdiv class=\"qm-faq-item\"\u003e\n        \u003cp class=\"qm-faq-q\"\u003eWhat is the CAS number of PFI-6-COOH?\u003c\/p\u003e\n        \u003cp\u003eThe CAS number of PFI-6-COOH is 2768514-05-0.\u003c\/p\u003e\n      \u003c\/div\u003e\n\n      \u003cdiv class=\"qm-faq-item\"\u003e\n        \u003cp class=\"qm-faq-q\"\u003eWhat is the molecular formula of PFI-6-COOH?\u003c\/p\u003e\n        \u003cp\u003eThe molecular formula listed for PFI-6-COOH is C23H21N3O6.\u003c\/p\u003e\n      \u003c\/div\u003e\n\n      \u003cdiv class=\"qm-faq-item\"\u003e\n        \u003cp class=\"qm-faq-q\"\u003eWhat is the molecular weight of PFI-6-COOH?\u003c\/p\u003e\n        \u003cp\u003eThe molecular weight listed for PFI-6-COOH is 435.43.\u003c\/p\u003e\n      \u003c\/div\u003e\n\n      \u003cdiv class=\"qm-faq-item\"\u003e\n        \u003cp class=\"qm-faq-q\"\u003eIs PFI-6-COOH related to ENL research?\u003c\/p\u003e\n        \u003cp\u003eYes. PFI-6-COOH is described in the product context as an ENL ligand relevant to epigenetic reader-domain and PROTAC research workflows.\u003c\/p\u003e\n      \u003c\/div\u003e\n\n      \u003cdiv class=\"qm-faq-item\"\u003e\n        \u003cp class=\"qm-faq-q\"\u003eIs PFI-6-COOH used in PROTAC synthesis workflows?\u003c\/p\u003e\n        \u003cp\u003eYes. PFI-6-COOH is used in research planning for ENL-targeting PROTAC synthesis workflows, including MS41-related literature context.\u003c\/p\u003e\n      \u003c\/div\u003e\n\n      \u003cdiv class=\"qm-faq-item\"\u003e\n        \u003cp class=\"qm-faq-q\"\u003eAre hazard statements confirmed for PFI-6-COOH?\u003c\/p\u003e\n        \u003cp\u003eNo compound-specific GHS hazard statements were found in the checked neutral sources.\u003c\/p\u003e\n      \u003c\/div\u003e\n\n      \u003cdiv class=\"qm-faq-item\"\u003e\n        \u003cp class=\"qm-faq-q\"\u003eIs PFI-6-COOH for research use only?\u003c\/p\u003e\n        \u003cp\u003eYes. PFI-6-COOH is supplied for laboratory research use only and is not intended for human, veterinary, food, drug, or household use.\u003c\/p\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n\n    \u003cdiv class=\"qm-section\"\u003e\n      \u003ch3\u003eNeutral references\u003c\/h3\u003e\n      \u003cul class=\"qm-ref-list\"\u003e\n        \u003cli\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37944866\/\" target=\"_blank\" rel=\"noopener noreferrer\"\u003ePubMed: Discovery of PFI-6, a small-molecule chemical probe for MLLT1\/3 YEATS domains\u003c\/a\u003e\u003c\/li\u003e\n        \u003cli\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39196923\/\" target=\"_blank\" rel=\"noopener noreferrer\"\u003ePubMed: A potent and selective ENL degrader suppresses oncogenic gene expression and leukemia progression\u003c\/a\u003e\u003c\/li\u003e\n        \u003cli\u003e\u003ca href=\"https:\/\/www.science.org\/doi\/10.1126\/sciadv.ado1432\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eScience Advances article on ENL degrader MS41\u003c\/a\u003e\u003c\/li\u003e\n      \u003c\/ul\u003e\n    \u003c\/div\u003e\n\n    \u003cdiv class=\"qm-disclaimer\"\u003e\n      For laboratory research use only. Not for human, veterinary, food, drug, or household use.\n    \u003c\/div\u003e\n  \u003c\/div\u003e\n\n  \u003cscript type=\"application\/ld+json\"\u003e\n  {\n    \"@context\": \"https:\/\/schema.org\",\n    \"@type\": \"FAQPage\",\n    \"mainEntity\": [\n      {\n        \"@type\": \"Question\",\n        \"name\": \"What is PFI-6-COOH used for?\",\n        \"acceptedAnswer\": {\n          \"@type\": \"Answer\",\n          \"text\": \"PFI-6-COOH is used in research workflows involving ENL ligand chemistry and PROTAC-related synthesis planning.\"\n        }\n      },\n      {\n        \"@type\": \"Question\",\n        \"name\": \"What is the CAS number of PFI-6-COOH?\",\n        \"acceptedAnswer\": {\n          \"@type\": \"Answer\",\n          \"text\": \"The CAS number of PFI-6-COOH is 2768514-05-0.\"\n        }\n      },\n      {\n        \"@type\": \"Question\",\n        \"name\": \"What is the molecular formula of PFI-6-COOH?\",\n        \"acceptedAnswer\": {\n          \"@type\": \"Answer\",\n          \"text\": \"The molecular formula listed for PFI-6-COOH is C23H21N3O6.\"\n        }\n      },\n      {\n        \"@type\": \"Question\",\n        \"name\": \"What is the molecular weight of PFI-6-COOH?\",\n        \"acceptedAnswer\": {\n          \"@type\": \"Answer\",\n          \"text\": \"The molecular weight listed for PFI-6-COOH is 435.43.\"\n        }\n      },\n      {\n        \"@type\": \"Question\",\n        \"name\": \"Is PFI-6-COOH related to ENL research?\",\n        \"acceptedAnswer\": {\n          \"@type\": \"Answer\",\n          \"text\": \"Yes. 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