{"product_id":"sr17018-2134602-45-0","title":"SR17018 [CAS 2134602-45-0]","description":"\u003cp\u003e\u003cstrong\u003eSR17018\u003c\/strong\u003e (CAS 2134602-45-0) is a certified reference standard supplied by Quantimol for laboratory and scientific research.\u003c\/p\u003e\u003cp\u003eSR17018 is a G protein-biased mu-opioid receptor (MOR) agonist with an EC50 of 97 nM (GTPγS binding assay). Biased MOR agonists preferentially activate G protein signalling over β-arrestin recruitment, a mechanism associated with reduced opioid side effects such as respiratory depression and tolerance. SR17018 is a key tool compound in the study of opioid receptor pharmacology and the development of safer analgesics.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eKey properties:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eTarget: Mu-opioid receptor (MOR \/ OPRM1)\u003c\/li\u003e\n\u003cli\u003eMechanism: G protein-biased MOR agonist\u003c\/li\u003e\n\u003cli\u003eCAS Number: 2134602-45-0\u003c\/li\u003e\n\u003cli\u003eEC50: 97 nM (GTPγS binding)\u003c\/li\u003e\n\u003cli\u003ePurity: ≥98% (HPLC)\u003c\/li\u003e\n\u003cli\u003eStorage: -20°C, protected from light\u003c\/li\u003e\n\u003cli\u003eSolubility: DMSO (recommended)\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eApplications:\u003c\/strong\u003e Opioid receptor pharmacology, biased agonism research, pain biology, analgesic drug discovery, β-arrestin vs G protein signalling studies.\u003c\/p\u003e\u003cp\u003eSupplied by Quantimol as a certified reference standard for research use only. Not for human or veterinary use.\u003c\/p\u003e","brand":"Quantimol","offers":[{"title":"5 mg","offer_id":53366226616657,"sku":"QM-0137074-01","price":103.75,"currency_code":"GBP","in_stock":true},{"title":"10 mM - 1 mL","offer_id":53366226649425,"sku":"QM-0137074-02","price":111.63,"currency_code":"GBP","in_stock":true},{"title":"10 mg","offer_id":53366226682193,"sku":"QM-0137074-03","price":188.51,"currency_code":"GBP","in_stock":true},{"title":"25 mg","offer_id":53366226714961,"sku":"QM-0137074-04","price":351.32,"currency_code":"GBP","in_stock":true},{"title":"50 mg","offer_id":53366226747729,"sku":"QM-0137074-05","price":539.64,"currency_code":"GBP","in_stock":true},{"title":"100 mg","offer_id":53366226780497,"sku":"QM-0137074-06","price":828.82,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1030\/0211\/2337\/files\/quantimol-021.png?v=1773515276","url":"https:\/\/quantimol.com\/products\/sr17018-2134602-45-0","provider":"Quantimol","version":"1.0","type":"link"}