{"product_id":"trimidox-hydrochloride-95933-75-8","title":"Trimidox (hydrochloride) [CAS 95933-75-8]","description":"\u003cp\u003e\u003cstrong\u003eTrimidox (hydrochloride)\u003c\/strong\u003e (CAS 95933-75-8) is a certified reference standard supplied by Quantimol for laboratory and scientific research.\u003c\/p\u003e\u003cp\u003eAlso known as VF-233, Trimidox hydrochloride is a potent ribonucleotide reductase (RNR) inhibitor with antileukemic activity. It inhibits the growth of human promyelocytic leukaemia HL-60 cells with an IC50 of 35 μM. Ribonucleotide reductase is a key enzyme in de novo deoxyribonucleotide synthesis, making RNR inhibitors important tools in cancer biology and antiviral research.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eKey properties:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eTarget: Ribonucleotide reductase (RNR)\u003c\/li\u003e\n\u003cli\u003eMechanism: RNR inhibitor\u003c\/li\u003e\n\u003cli\u003eCAS Number: 95933-75-8\u003c\/li\u003e\n\u003cli\u003eIC50: 35 μM (HL-60 cells)\u003c\/li\u003e\n\u003cli\u003ePurity: ≥98% (HPLC)\u003c\/li\u003e\n\u003cli\u003eStorage: -20°C, protected from light\u003c\/li\u003e\n\u003cli\u003eSolubility: Water or DMSO (recommended)\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eApplications:\u003c\/strong\u003e Ribonucleotide reductase inhibition, antileukemic research, DNA synthesis studies, cancer cell biology, antiviral drug discovery.\u003c\/p\u003e\u003cp\u003eSupplied by Quantimol as a certified reference standard for research use only. Not for human or veterinary use.\u003c\/p\u003e","brand":"Quantimol","offers":[{"title":"1 mg","offer_id":53308184789329,"sku":"QM-0104180-01","price":90.25,"currency_code":"GBP","in_stock":true},{"title":"5 mg","offer_id":53308184822097,"sku":"QM-0104180-02","price":227.39,"currency_code":"GBP","in_stock":true},{"title":"10 mg","offer_id":53308184854865,"sku":"QM-0104180-03","price":379.26,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1030\/0211\/2337\/files\/quantimol-021.png?v=1773515276","url":"https:\/\/quantimol.com\/products\/trimidox-hydrochloride-95933-75-8","provider":"Quantimol","version":"1.0","type":"link"}