{"product_id":"uv-cleavable-biotin-peg2-azide-1192802-98-4","title":"UV Cleavable Biotin-PEG2-Azide [CAS 1192802-98-4]","description":"\u003cp\u003e\u003cstrong\u003eUV Cleavable Biotin-PEG2-Azide\u003c\/strong\u003e (CAS 1192802-98-4) is a certified click chemistry reagent supplied by Quantimol for laboratory and scientific research.\u003c\/p\u003e\u003cp\u003eThis compound is a photocleavable biotin-PEG-azide bifunctional reagent featuring a UV-cleavable nitrobenzyl linker, a PEG2 spacer, and a terminal azide group. It is widely used as a PROTAC linker and in bioorthogonal chemistry workflows. The azide group enables copper-catalysed azide-alkyne cycloaddition (CuAAC) with alkyne-bearing molecules, as well as strain-promoted azide-alkyne cycloaddition (SPAAC) with DBCO or BCN groups. UV irradiation cleaves the nitrobenzyl linker, releasing the biotinylated cargo for downstream streptavidin-based capture or detection.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eKey properties:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eReactive group: Azide (click chemistry)\u003c\/li\u003e\n\u003cli\u003eCleavage: UV-cleavable nitrobenzyl linker (365 nm)\u003c\/li\u003e\n\u003cli\u003eAffinity tag: Biotin (streptavidin-compatible)\u003c\/li\u003e\n\u003cli\u003eSpacer: PEG2\u003c\/li\u003e\n\u003cli\u003eCAS Number: 1192802-98-4\u003c\/li\u003e\n\u003cli\u003ePurity: ≥95% (HPLC)\u003c\/li\u003e\n\u003cli\u003eStorage: -20°C, protected from light\u003c\/li\u003e\n\u003cli\u003eSolubility: DMSO (recommended)\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eApplications:\u003c\/strong\u003e PROTAC linker synthesis, CuAAC and SPAAC click chemistry, photoaffinity labelling, streptavidin pull-down assays, chemical proteomics, bioorthogonal bioconjugation.\u003c\/p\u003e\u003cp\u003eSupplied by Quantimol as a certified reference standard for research use only. Not for human or veterinary use.\u003c\/p\u003e","brand":"Quantimol","offers":[{"title":"10 mg","offer_id":53345856586065,"sku":"QM-0147293-01","price":464.31,"currency_code":"GBP","in_stock":true},{"title":"25 mg","offer_id":53345856618833,"sku":"QM-0147293-02","price":565.16,"currency_code":"GBP","in_stock":true},{"title":"100 mg","offer_id":53345856651601,"sku":"QM-0147293-03","price":1380.42,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1030\/0211\/2337\/files\/quantimol-021.png?v=1773515276","url":"https:\/\/quantimol.com\/products\/uv-cleavable-biotin-peg2-azide-1192802-98-4","provider":"Quantimol","version":"1.0","type":"link"}