1,11b-Dihydro-11b-hydroxymedicarpin [CAS 210537-04-5]
1,11b-Dihydro-11b-hydroxymedicarpin [CAS 210537-04-5]
SKU:QM-0163437-01
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Product Details
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Description
1,11b-Dihydro-11b-hydroxymedicarpin (11b-Hydroxy-11b,1-dihydromedicarpin) is a pterocarpan from Ononis viscosa subsp. breviflora is a Medicarpin derivative[1]. Medicarpin, a natural pterocarpan, heals cortical bone defect by activation of Notch and Wnt canonical signaling pathways[2]. Medicarpin prevents arthritis in post-menopausal conditions by arresting the expansion of TH17 cells and pro-inflammatory cytokines. Medicarpin down-regulates pro-inflammatory cytokines like TNF-α, IL-6 and IL-17A, while up-regulates anti-inflammatory cytokine IL-10 in arthritis (CIA) model of mice[3].
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CAS Number
[210537-04-5]
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Molecular Formula
C16H16O5
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Molecular Weight
288.3
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Smiles
O=C(CC1)C=C2[C@@]1(O)[C@@](OC3=CC(OC)=CC=C34)([H])[C@@]4([H])CO2
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Target
Interleukin Related; Wnt
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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1,11b-Dihydro-11b-hydroxymedicarpin [CAS 210537-04-5]
1,11b-Dihydro-11b-hydroxymedicarpin is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.