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1,3,5-Trihydroxy-4-prenylxanthone [CAS 53377-61-0]
1,3,5-Trihydroxy-4-prenylxanthone [CAS 53377-61-0]
SKU:QM-0086367
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Product Details
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Description
1,3,5-Trihydroxy-4-prenylxanthone is a Na+/H+ exchange system inhibitor with a minimum inhibitory concentration of 10 μg/mL[1]. 1,3,5-Trihydroxy-4-prenylxanthone is a phosphodiesterase type 5 (PDE5) inhibitor with an IC50 value of 3.0 μM[3]. 1,3,5-Trihydroxy-4-prenylxanthone inhibits Lipopolysaccharide (LPS) -induced NO production in RAW264.7 macrophages, and has anti-inflammatory activities[2].
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CAS Number
[53377-61-0]
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Molecular Formula
C18H16O5
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Molecular Weight
312.32
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Smiles
C/C(C)=C\CC1=C2C(C(C3=C(C(O)=CC=C3)O2)=O)=C(O)C=C1O
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Target
Na+/H+ Exchanger (NHE) ; NO Synthase; Phosphodiesterase (PDE)
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Isoform
INOS; PDE5
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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1,3,5-Trihydroxy-4-prenylxanthone [CAS 53377-61-0]
1,3,5-Trihydroxy-4-prenylxanthone is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.