1,8-Dihydroxy-4,5-dinitroanthraquinone [CAS 81-55-0]
1,8-Dihydroxy-4,5-dinitroanthraquinone [CAS 81-55-0]
SKU:QM-0140145-01
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Product Details
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Description
1,8-Dihydroxy-4,5-dinitroanthraquinone (ARDP0006; DHDNE) is a potent inhibitor of serine proteinase NS2B/3, the dengue viral protein. 1,8-Dihydroxy-4,5-dinitroanthraquinone has intermolecular proteinase activity and viral inhibition ability with IC50s of 432 μM and 4.2 μM, respectively. Meanwhile 1,8-Dihydroxy-4,5-dinitroanthraquinone inhibits NS2B/3 cleavage in BHK-21 cells at a dose ranging from 4.2 μM to 432 μM[1].
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CAS Number
[81-55-0]
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Molecular Formula
C14H6N2O8
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Molecular Weight
330.21
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Smiles
O=C1C2=C(C(C3=C(C=CC(O)=C13)[N+]([O-])=O)=O)C([N+]([O-])=O)=CC=C2O
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Target
Dengue Virus; Flavivirus; Virus Protease
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Concentration
10mM
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Purity
98.03
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Solubility
DMSO : 41.67 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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Hazard Statement
H315, H319, H335
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Precautions
H315, H319, H335
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1,8-Dihydroxy-4,5-dinitroanthraquinone [CAS 81-55-0]
1,8-Dihydroxy-4,5-dinitroanthraquinone is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.