1-Arachidonoyl-2-hydroxy-sn-glycero-3-PA [CAS 65446-08-4]
1-Arachidonoyl-2-hydroxy-sn-glycero-3-PA [CAS 65446-08-4]
SKU:QM-0010139
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Product Details
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Description
1-Arachidonoyl-2-hydroxy-sn-glycero-3-PA is a phospholipid containing arachidonic acid at the sn-1 position. It is a precursor to 1-arachidonoyl glycerol (1-Monoarachidin; HY-130567). 1-Arachidonoyl-2-hydroxy-sn-glycero-3-PA binds to the LPA2/EDG4 receptor with an EC50 value of approximately 10 nM[2]. It prevents TNF-α and IL-6 secretion in wild-type but not Lpa2-/- dendritic cells stimulated by LPS[3]. It also decreases differentiation of HT-29 human colon carcinoma cells to goblet cells in the presence of sodium butyrate[4].
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CAS Number
[65446-08-4]
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Molecular Formula
C23H39O7P
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Molecular Weight
458.53
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Smiles
O=P(O)(O)OC[C@H](O)COC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O
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Target
LPL Receptor
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Shipping Conditions
Room temperature
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1-Arachidonoyl-2-hydroxy-sn-glycero-3-PA [CAS 65446-08-4]
1-Arachidonoyl-2-hydroxy-sn-glycero-3-PA is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.