10-Deacetyltaxol [CAS 78432-77-6]
10-Deacetyltaxol [CAS 78432-77-6]
SKU:QM-0164243-01
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Product Details
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Description
10-Deacetyltaxol (10-Deacetylpaclitaxel) is a taxane derivative isolated from Taxus wallichiana Zucc[1]. 10-Deacetyltaxol (10-Deacetylpaclitaxel) promotes the polymerization of tubulin and to inhibit the depolymerization of microtubules induced by cold or by calcium ions in vitro[2]. 10-Deacetyltaxol (10-Deacetylpaclitaxel) exhibits cytotoxicity in human glial and neuroblastoma cell-lines[3].
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CAS Number
[78432-77-6]
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Molecular Formula
C45H49NO13
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Molecular Weight
811.87
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Smiles
CC(O[C@]12[C@@]([C@]3([C@@H](O)C[C@@]1([H])OC2)C)([H])[C@@H]([C@]4(C(C)(C([C@@H](O)C3=O)=C(C)[C@@H](OC([C@H](O)[C@H](C5=CC=CC=C5)NC(C6=CC=CC=C6)=O)=O)C4)C)O)OC(C7=CC=CC=C7)=O)=O
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Target
Microtubule/Tubulin
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Purity
99.72
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Solubility
DMSO : 125 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302
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Precautions
H302
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10-Deacetyltaxol [CAS 78432-77-6]
10-Deacetyltaxol is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.