103D5R [CAS 773852-25-8]

103D5R (Compound 15) is an inhibitor for the activation of hypoxia-inducible factor-1 (HIF-1) with an IC50 of 35 µM, through reduction of the HIF-1α protein synthesis. 103D5R inhibits the proliferation of LN229 with IC50 of 26 µM[1].

[773852-25-8]

C20H21N3O2

335.4

CC(N1C=NC2=NC=CC=C21)C3=CC=C4C(C=CC(C)(C)O4)=C3OC

HIF/HIF Prolyl-Hydroxylase

Room temperature