12-Oxo-leukotriene B4 [CAS 136696-10-1]
12-Oxo-leukotriene B4 [CAS 136696-10-1]
SKU:QM-0127864-01
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Product Details
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Description
12-Oxo-leukotriene B4 (12-Oxo-LTB4) is an intermediate in the lipoxygenase-catalyzed path of Arachidonic acid metabolism. 12-Oxo-leukotriene B4 is crucial in Leukotriene B4 metabolism and is involved in inflammation reactions[1]. 12-Oxo-leukotriene B4 stimulates calcium levels in human neutrophils with an EC50 of 33 nM. 12-Oxo-leukotriene B4 induces migration of neutrophils with EC50 of 170 nM[2].
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CAS Number
[136696-10-1]
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Molecular Formula
C20H30O4
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Molecular Weight
334.45
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Smiles
CCCCC/C=C\CC(/C=C/C=C/C=C\[C@@H](O)CCCC(O)=O)=O
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Target
Endogenous Metabolite
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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12-Oxo-leukotriene B4 [CAS 136696-10-1]
12-Oxo-leukotriene B4 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.