14-Acetoxy parthenolide [CAS 2064236-08-2]

14-Acetoxy parthenolide (compound 6a) is a parthenolide (PTL) derivative. 14-Acetoxy parthenolide exhibits potent anti-acute myeloid leukemia (AML) activity against HL-60 and KG1a cells, with IC50 values of 2.8 µM and 6.3 µM, respectively. 14-Acetoxy parthenolide can be used for AML research[1].

[2064236-08-2]

C17H22O5

306.35

[H][C@]12O[C@]1(C)CC/C=C(CC[C@]3(C(C(O[C@@]32[H])=O)=C)[H])/COC(C)=O

Drug Derivative

Room temperature