14-Deoxyandrographolide [CAS 4176-97-0]

14-Deoxyandrographolide is a diterpene with calcium channel blocking activity and acts as a uterine smooth muscle relaxant. 14-Deoxyandrographolide stimulates the release of nitric oxide (NO) in endothelial cells. 14-Deoxyandrographolide gradually desensitizes liver cells to TNF-α mediated apoptosis by inducing the release of TNFRSF1A[1][2][3].

[4176-97-0]

C20H30O4

334.45

O=C1OCC=C1CC[C@@H]2C(CC[C@]3([H])[C@](C)(CO)[C@H](O)CC[C@@]23C)=C

Apoptosis; Calcium Channel; Caspase

Caspase 3

99.94

DMSO : 100 mg/mL (ultrasonic)

4°C (Powder, protect from light)

Room Temperature