15 (R) -Lipoxin A4 [CAS 171030-11-8]

15 (R) -Lipoxin A4 (15-epi-LXA4) is a STAT-6 activator and a lipid-derived lipoxin-type specialized pro-resolving mediator (SPM) that plays a role in promoting inflammation resolution and regulating immune cell function. 15 (R) -Lipoxin A4 can improve the phagocytic function of microglia and exhibits anti-inflammatory activity. In Alzheimer's disease (AD) mouse models, 15 (R) -Lipoxin A4 improves AD-like pathology. 15 (R) -Lipoxin A4 holds potential for use in inflammation and neurodegenerative disease research[1].

[171030-11-8]

C20H32O5

352.47

CCCCC[C@@H](O)/C=C/C=C\C=C\C=C\[C@@H](O)[C@@H](O)CCCC(O)=O

STAT

STAT6

283.71 μM * 250 μL in Ethanol

98.3

Solution, -20°C, 2 years

Blue Ice

H225, H319

H225, H319