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16-Hydroxycleroda-3,13-dien-15,16-olide [CAS 141979-19-3]
16-Hydroxycleroda-3,13-dien-15,16-olide [CAS 141979-19-3]
SKU:QM-0100282
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Product Details
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Description
16-Hydroxycleroda-3,13-dien-15,16-olide (16ξ-Hydroxycleroda-3,13-dien-15,16-olide; HCD), a clerodane diterpene, is a potent serine protease dipeptidyl peptidase 4 (DPP-4) inhibitor. 16-Hydroxycleroda-3,13-dien-15,16-olide down-regulates LPS-induced ERK phosphorylation in myocyte but blocks GLP-1 induced PKA expression. 16-Hydroxycleroda-3,13-dien-15,16-olide exhibits hypolipidemic, hepatoprotective, hypoglycemic efficacy[1].
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CAS Number
[141979-19-3]
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Molecular Formula
C20H30O3
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Molecular Weight
318.45
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Smiles
OC(O1)C(CC[C@@]2([C@]3([H])[C@@](CC[C@H]2C)(C(C)=CCC3)C)C)=CC1=O
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Target
Dipeptidyl Peptidase
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Isoform
DPP-4
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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16-Hydroxycleroda-3,13-dien-15,16-olide [CAS 141979-19-3]
16-Hydroxycleroda-3,13-dien-15,16-olide is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.