16α-Hydroxyprednisolone [CAS 13951-70-7]
16α-Hydroxyprednisolone [CAS 13951-70-7]
SKU:QM-0076203-01
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Product Details
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Description
16α-Hydroxyprednisolone (OH-PRED) is a stereoselective metabolite of the 22 (R) epimer of the glucocorticoid Budesonide. 16α-Hydroxyprednisolone formation is catalyzed by isoenzymes within the cytochrome P450 3A (CYP3A) subfamily. 16α-Hydroxyprednisolone formation can be inhibited by antibodies targeting the CYP3A subfamily[1][2].
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CAS Number
[13951-70-7]
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Molecular Formula
C21H28O6
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Molecular Weight
376.44
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Smiles
O=C1C=C[C@@]2([C@]3([C@H](C[C@@]4([C@](O)([C@@H](C[C@]4([C@@]3(CCC2=C1)[H])[H])O)C(CO)=O)C)O)[H])C
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Target
Drug Metabolite
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Purity
99.78
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, protect from light)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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16α-Hydroxyprednisolone [CAS 13951-70-7]
16α-Hydroxyprednisolone is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.