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2′,2′-Difluorodeoxyuridine [CAS 114248-23-6]
2′,2′-Difluorodeoxyuridine [CAS 114248-23-6]
SKU:QM-0146234-01
£63.82 GBP
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Product Details
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Description
2’,2’-Difluorodeoxyuridine (dFdU) is the main metabolite of Gemcitabine. 2’,2’-Difluorodeoxyuridine causes a concentration- and schedule- dependent radiosensitising effect in vitro. 2’,2’-Difluorodeoxyuridine arrests cell cycle at the early S phase and induces apoptosis in cancer cells[1][2][3].
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CAS Number
[114248-23-6]
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Molecular Formula
C9H10F2N2O5
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Molecular Weight
264.18
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Smiles
O=C(N1)N([C@@H]2O[C@H](CO)[C@@H](O)C2(F)F)C=CC1=O
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Target
Apoptosis; Drug Metabolite
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Purity
99.87
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Solubility
DMSO : 125 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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Hazard Statement
H315, H319, H335
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Precautions
H315, H319, H335
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2′,2′-Difluorodeoxyuridine [CAS 114248-23-6]
2′,2′-Difluorodeoxyuridine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.