2′,2′-Difluorodeoxyuridine-13C,15N2 [CAS 1233921-75-9]
2′,2′-Difluorodeoxyuridine-13C,15N2 [CAS 1233921-75-9]
SKU:QM-0063305
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Product Details
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Description
2′,2′-Difluorodeoxyuridine-13C,15N2 (dFdU-13C,15N2) is a 13C- and 15N-labeled compound. 2’,2’-Difluorodeoxyuridine (dFdU) is the main metabolite of Gemcitabine. 2’,2’-Difluorodeoxyuridine causes a concentration- and schedule- dependent radiosensitising effect in vitro. 2’,2’-Difluorodeoxyuridine arrests cell cycle at the early S phase and induces apoptosis in cancer cells[1][2][3][4].
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CAS Number
[1233921-75-9]
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Molecular Formula
C8 13CH10F2 15N2O5
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Molecular Weight
267.16
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Smiles
O=[13C]([15NH]1)[15N]([C@@H]2O[C@H](CO)[C@@H](O)C2(F)F)C=CC1=O
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Target
Apoptosis; Drug Metabolite; Isotope-Labeled Compounds
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Purity
99.5
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Solubility
10 mM in DMSO
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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2′,2′-Difluorodeoxyuridine-13C,15N2 [CAS 1233921-75-9]
2′,2′-Difluorodeoxyuridine-13C,15N2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.