2,3-Dihydrocalodenin B

2,3-Dihydrocalodenin B (Compound 6) is a compound that can be isolated from Knema globularia. 2,3-Dihydrocalodenin B is a potent and non-competitive inhibitor against α-glucosidase and α-amylase, with IC50 values of 1.1 and 2.6 μM, respectively. 2,3-Dihydrocalodenin B can be used for the research of diabetes[1].

C30H22O9

526.49

OC1=CC(O)=C([C@H](C(C2=C(O)C=C(O)C=C2)=O)[C@@H](C3=CC=C(O)C=C3)O4)C4=C1C(/C=C/C5=CC=C(O)C=C5)=O

Amylases; Glycosidase

10 mM in DMSO

Room temperature