2,4′-Dihydroxybenzophenone [CAS 131-56-6]
2,4′-Dihydroxybenzophenone [CAS 131-56-6]
SKU:QM-0202758-01
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Product Details
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Description
2,4′-Dihydroxybenzophenone (Ultraviolet absorber UV-0) occupies the hydrophobic pocket of MD2 and blocks the dimerization of TLR4. 2,4′-Dihydroxybenzophenone inhibits the LPS induced mtROS production, and LPS induced inflammatory response by downregulating pro-inflammatory mediators and decreasing the expression of MyD88, p-IRAK4, and NF-κB. 2,4′-Dihydroxybenzophenone is also a UV absorber[1][2].
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CAS Number
[131-56-6]
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Molecular Formula
C13H10O3
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Molecular Weight
214.22
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Smiles
OC1=CC(O)=C(C(C2=CC=CC=C2)=O)C=C1
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Target
IRAK; MyD88; NF-κB; Reactive Oxygen Species (ROS) ; Toll-like Receptor (TLR)
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Purity
98
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Solubility
DMSO : 200 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H319, H361, H411
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Precautions
H319, H361, H411
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2,4′-Dihydroxybenzophenone [CAS 131-56-6]
2,4′-Dihydroxybenzophenone is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.