2,6-Dihydroxyacetophenone [CAS 699-83-2]
2,6-Dihydroxyacetophenone [CAS 699-83-2]
SKU:QM-0200211-01
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Product Details
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Description
2,6-Dihydroxyacetophenone, a polyphenolic derivative of Acetophenone , is an orally active mTOR inhibitor. 2,6-Dihydroxyacetophenone shows antioxidant activity. 2,6-Dihydroxyacetophenone inhibits cell growth and proliferation in CRC cells. 2,6-Dihydroxyacetophenone arrests at G0/G1 phase of cell cycle, induces apoptosis and suppresses cell migration in CRC cells. 2,6-Dihydroxyacetophenone inhibits xanthine oxidase (XOD) with an IC50 of 1.24 mM. 2,6-dihydroxyacetophenone improves uric acid metabolism in hyperuricemia mice, reduces plasma cholesterol in hypercholesterolemic rats, and inhibits lipid accumulation in HFD-induced obese mice. 2,6-Dihydroxyacetophenone can be used for the study of colorectal cancer (CRC), hyperuricemia and hypercholesterolemia[1][2][3][4][5][6].
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CAS Number
[699-83-2]
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Molecular Formula
C8H8O3
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Molecular Weight
152.15
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Smiles
CC(C1=C(O)C=CC=C1O)=O
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Target
Apoptosis; mTOR; Xanthine Oxidase
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Concentration
10mM
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Purity
99.88
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, stored under nitrogen)
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Shipping Conditions
Room Temperature
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Hazard Statement
H315, H319, H335
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Precautions
H315, H319, H335
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2,6-Dihydroxyacetophenone [CAS 699-83-2]
2,6-Dihydroxyacetophenone is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.