2′-Azido-2′-deoxy-5-methyluridine [CAS 97748-75-9]
2′-Azido-2′-deoxy-5-methyluridine [CAS 97748-75-9]
SKU:QM-0071156
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Product Details
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Description
2′-Azido-2′-deoxy-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 2′-Azido-2′-deoxy-5-methyluridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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CAS Number
[97748-75-9]
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Molecular Formula
C10H13N5O5
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Molecular Weight
283.24
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Smiles
OC[C@@H]1[C@@H](O)[C@@H](N=[N+]=[N-])[C@H](N2C(NC(C(C)=C2)=O)=O)O1
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Target
Nucleoside Antimetabolite/Analog
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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2′-Azido-2′-deoxy-5-methyluridine [CAS 97748-75-9]
2′-Azido-2′-deoxy-5-methyluridine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.