2- (Azido-PEG3-amido) -1,3-bis (carboxylethoxy) propane [CAS 2086689-05-4]

2-Azido-PEG3-amido-13-biscarboxylethoxypropane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 2- (Azido-PEG3-amido) -1,3-bis (carboxylethoxy) propane is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

[2086689-05-4]

C18H32N4O10

464.47

O=C(O)CCOCC(COCCC(O)=O)NC(CCOCCOCCOCCN=[N+]=[N-])=O

PROTAC Linkers

PEG Linkers

10 mM in DMSO

Room temperature

H302-H315-H319-H335

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501