2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite [CAS 2245842-16-2]
2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite [CAS 2245842-16-2]
SKU:QM-0109982-01
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Product Details
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Description
2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly (ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia[1][2].
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CAS Number
[2245842-16-2]
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Molecular Formula
C40H46FN6O7P
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Molecular Weight
772.8
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Smiles
COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](F)[C@H](N5C(NC=NC6=O)=C6N=C5)O4
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Target
Nucleoside Antimetabolite/Analog; Xanthine Oxidase
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Purity
98.81
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, stored under nitrogen)
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Shipping Conditions
Room Temperature
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Hazard Statement
H315, H317, H319, H335, H360
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Precautions
H315, H317, H319, H335, H360
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2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite [CAS 2245842-16-2]
2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.