2-Me PeER

2-Me PeER is a rhodamine dye-based fluorescent probe that detects CYP3A4 activity. In fluorescence-activated cell sorting (FACS) based on CYP3A4 activity, homogeneous and functional human induced pluripotent stem cell (hiPSC) -derived hepatocytes and intestinal epithelial cells can be obtained with the aid of 2-Me PeER[1].

C31H37N2O4+

501.64

O=C(O)C(C=CC=C1)=C1C2=C(C=C/3)C(OC4=C2C=C(C)C(N(CCOCCCCC)C)=C4)=CC3=[N+](C)/C

Cytochrome P450

10 mM in DMSO

Room temperature