2'MeO6MF [CAS 89112-85-6]

2'MeO6MF is a brain-penetrant positive allosteric modulator at α2β1γ2L and all α1-containing GABAA receptors. 2'MeO6MF also can directly activate α2β2/3 and α2β2/3γ2L GABAA receptors. 2'MeO6MF has anxiolytic and psychomotor stabilizing properties. 2'MeO6MF offers neuroprotection and improved functional recovery and dampens the stroke-induced inflammatory response[1][2].

[89112-85-6]

C17H14O3

266.29

O=C1C=C(C2=CC=CC=C2OC)OC3=CC=C(C)C=C13

GABA Receptor

10 mM in DMSO

Room temperature