2-MeS-ADP (trisodium) [CAS 475193-31-8]
2-MeS-ADP (trisodium) [CAS 475193-31-8]
SKU:QM-0136184-01
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Product Details
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Description
2-Methylthioadenosine diphosphate trisodium is a potent purinergic P2Y receptors agonist, with EC50s of 19, 6.2, and 5 nM for human P2Y13, mouse P2Y13 and human P2Y12, respectively. 2-Methylthioadenosine diphosphate trisodium has pEC50s of 8.29 and 5.75 for human P2Y1 and rat P2Y6, respectively. 2-Methylthioadenosine diphosphate trisodium induces platelet aggregation and shape change, and inhibits cyclic AMP accumulation in platelets exposed to prostaglandin E1[1][2][3].
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CAS Number
[475193-31-8]
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Molecular Formula
C11H14N5Na3O10P2S
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Molecular Weight
539.24
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Smiles
O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=C(SC)N=C3N)O[C@@H]1COP(OP(O[Na])(O[Na])=O)(O[Na])=O
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Target
P2Y Receptor
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Isoform
P2Y12 Receptor; P2Y13 Receptor
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Concentration
10 mM * 185 μL in Water
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Purity
99.9
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Solubility
10 mM in DMSO
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Storage Conditions
Solution, -20°C, 2 years
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Shipping Conditions
Blue Ice
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2-MeS-ADP (trisodium) [CAS 475193-31-8]
2-MeS-ADP (trisodium) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.