2’-O-Acetyl-3’-azido-5’-O- (4-methylbenzoyl) -3’-deoxyuridine [CAS 256485-42-4]
2’-O-Acetyl-3’-azido-5’-O- (4-methylbenzoyl) -3’-deoxyuridine [CAS 256485-42-4]
SKU:QM-0071095
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Product Details
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Description
2’-O-Acetyl-3’-azido-5’-O- (4-methylbenzoyl) -3’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 2’-O-Acetyl-3’-azido-5’-O- (4-methylbenzoyl) -3’-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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CAS Number
[256485-42-4]
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Molecular Formula
C19H19N5O7
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Molecular Weight
429.38
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Smiles
O=C(C1=CC=C(C)C=C1)OC[C@@H]2[C@@H](N=[N+]=[N-])[C@@H](OC(C)=O)[C@H](N3C(NC(C=C3)=O)=O)O2
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Target
Nucleoside Antimetabolite/Analog
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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2’-O-Acetyl-3’-azido-5’-O- (4-methylbenzoyl) -3’-deoxyuridine [CAS 256485-42-4]
2’-O-Acetyl-3’-azido-5’-O- (4-methylbenzoyl) -3’-deoxyuridine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.