24 (S) -Hydroxycholesterol [CAS 474-73-7]
24 (S) -Hydroxycholesterol [CAS 474-73-7]
SKU:QM-0154275-01
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Product Details
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Description
24 (S) -Hydroxycholesterol (24S-OHC), the major brain cholesterol metabolite, plays an important role to maintain homeostasis of cholesterol in the brain. 24 (S) -Hydroxycholesterol (24S-OHC) is one of the most efficient endogenous LXR agonist known and is present in the brain and in the circulation at relatively high levels. 24 (S) -Hydroxycholesterol (24S-OHC) is a very potent, direct, and selective positive allosteric modulator of NMDARs with a mechanism that does not overlapthat of other allosteric modulators[1][2][3].
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CAS Number
[474-73-7]
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Molecular Formula
C27H46O2
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Molecular Weight
402.65
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Smiles
C[C@H](CC[C@H](O)C(C)C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C
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Target
Endogenous Metabolite; iGluR; LXR
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Isoform
Human Endogenous Metabolite; NMDA Receptor
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Purity
99.75
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Solubility
DMSO : 12.5 mg/mL (ultrasonic) |Ethanol : 20 mg/mL (ultrasonic; warming)
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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24 (S) -Hydroxycholesterol [CAS 474-73-7]
24 (S) -Hydroxycholesterol is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.