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28-Deoxonimbolide [CAS 126005-94-5]
28-Deoxonimbolide [CAS 126005-94-5]
SKU:QM-0093932
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Product Details
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Description
28-Deoxonimbolide is a Nimbin type limonoid, that can be isolated from Azadirachta indica seed extracts. 28-Deoxonimbolide shows anticancer activity. 28-Deoxonimbolide induces apoptotic cell death in HL60 cells via both the mitochondrial- and the death receptor-mediated pathways[1].
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CAS Number
[126005-94-5]
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Molecular Formula
C27H32O6
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Molecular Weight
452.54
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Smiles
O=C(OC)C[C@@H]([C@]1(C)C2=C(C)[C@H](C3=COC=C3)C[C@@]2([H])O[C@]1([H])[C@@](OC4)([H])[C@@]5([H])[C@@]4(C)C=C6)[C@@]5(C)C6=O
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Target
Apoptosis; Caspase
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Isoform
Caspase 3; Caspase 8; Caspase 9
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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28-Deoxonimbolide [CAS 126005-94-5]
28-Deoxonimbolide is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.