2DII

2DII is a potent and selective mTORC2 inhibitor. 2DII selectively binds mSin1 PH domain and decreases the expression of AKT1 phosphorylation[1].

C54H76ClN7O11S

1066.74

O=C([C@H]1N(C(C2=CC=C(OC)C(S(=O)(NCC3=CC=C(Cl)C=C3)=O)=C2)=O)CCC1)N[C@H](C(NCCOCCOCC(N[C@H](C(N)=O)CNC(CCCCCCC/C=C\CCCCCC)=O)=O)=O)CC4=CC=CC=C4

MTOR

98.92

DMSO : 100 mg/mL (ultrasonic)

-20°C, 3 years (Powder)

Blue Ice