(2R,3S) -Azelaprag [CAS 2049979-31-7]

(2R,3S) -Azelaprag ((2R,3S) -AMG 986) (Example 238.0) is a precursor of an apelin receptor agonist (EC50=12 nM) and an isomer of Azelaprag.

[2049979-31-7]

C25H29N7O4S

523.61

O=S(NC1=NN=C(C2=CN=CC(C)=C2)N1C(C(OC)=CC=C3)=C3OC)([C@H](C)[C@H](C4=NC=C(C)C=N4)C)=O

Apelin Receptor (APJ) ; Drug Isomer

99.1

DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature