(2R,3S) -Emricasan [CAS 409369-54-6]

(2R,3S) -Emricasan ((2R,3S) -PF 03491390) is an isomer of Emricasan. Emricasan is an orally active and irreversible pan-caspase inhibitor. Emricasan inhibits Zika virus (ZIKV) -induced increases in caspase-3 activity and protected human cortical neural progenitors[1].

[409369-54-6]

C26H27F4N3O7

569.5

FC1=C(C(F)=C(C=C1F)F)OCC([C@@H](NC([C@H](NC(C(NC2=C(C=CC=C2)C(C)(C)C)=O)=O)C)=O)CC(O)=O)=O

Caspase; Flavivirus

Room temperature