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(2R,4R) -1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate [CAS 114676-69-6]
(2R,4R) -1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate [CAS 114676-69-6]
SKU:QM-0199269-01
£52.94 GBP
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Product Details
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Description
N-Boc-cis-4-hydroxy-D-proline methyl ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . N-Boc-cis-4-hydroxy-D-proline methyl ester is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1
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CAS Number
[114676-69-6]
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Molecular Formula
C11H19NO5
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Molecular Weight
245.28
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Smiles
CC(C)(C)OC(N1[C@H](C[C@H](C1)O)C(OC)=O)=O
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Target
ADC Linker; PROTAC Linkers
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Isoform
Non-cleavable Linker
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Purity
99.96
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Solubility
10 mM in DMSO
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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(2R,4R) -1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate [CAS 114676-69-6]
(2R,4R) -1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.