3,4-Dichloroisocoumarin [CAS 51050-59-0]
3,4-Dichloroisocoumarin [CAS 51050-59-0]
SKU:QM-0141727-01
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Product Details
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Description
3,4-Dichloroisocoumarin is a potent serine-protease and SrLip inhibitor (Ki for SrLip: 26.6 μM) . 3,4-Dichloroisocoumarin is opened by serine proteases and then undergoes acylation with the enzyme, thereby inhibiting protease activity. 3,4-Dichloroisocoumarin can induce DNA fragmentation and Apoptosis. 3,4-Dichloroisocoumarin can be used in the research of multiple fields such as tumors, cardiovascular disease and enzyme catalytic mechanisms[1][2][3][4][5].
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CAS Number
[51050-59-0]
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Molecular Formula
C9H4Cl2O2
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Molecular Weight
215.03
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Smiles
ClC1=C(OC(C2=C1C=CC=C2)=O)Cl
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Target
Apoptosis; Ser/Thr Protease
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Purity
99.72
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H301, H315, H319, H335
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Precautions
H301, H315, H319, H335
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3,4-Dichloroisocoumarin [CAS 51050-59-0]
3,4-Dichloroisocoumarin is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.