3,7-Dihydroxyflavone [CAS 492-00-2]
3,7-Dihydroxyflavone [CAS 492-00-2]
SKU:QM-0088956-01
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Product Details
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Description
3,7-Dihydroxyflavone (Resogalangin) is a flavonoid phytoestrogen, which can be isolated from Adenophora species. 3,7-Dihydroxyflavone is a modulator of estrogen receptors and an inhibitor of human progesterone metabolizing enzyme AKR1C1 and fungal 17β-hydroxysteroid dehydrogenase and a redox inhibitor (IC50=0.6 and 6.0 μM, respectively) . 3,7-Dihydroxyflavone is a fluorescent binding substrate for human serum albumin (HSA) with excitation wavelengths of 370 nm (pH 7.4) and 350 nm (pH 3.5), respectively, and emission wavelength of 515 nm[1][2].
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CAS Number
[492-00-2]
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Molecular Formula
C15H10O4
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Molecular Weight
254.24
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Smiles
O=C1C(O)=C(C2=CC=CC=C2)OC3=CC(O)=CC=C13
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Target
17β-HSD; Aldose Reductase; Estrogen Receptor/ERR
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Purity
98.04
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Solubility
DMSO : 70 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H315, H319
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Precautions
H315, H319
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3,7-Dihydroxyflavone [CAS 492-00-2]
3,7-Dihydroxyflavone is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.