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3’-Azido-3’-deoxy-N6-methyladenosine [CAS 889126-08-3]

3’-Azido-3’-deoxy-N6-methyladenosine [CAS 889126-08-3]

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SKU:QM-0069928

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  • Description

    3’-Azido-3’-deoxy-N6-methyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 3’-Azido-3’-deoxy-N6-methyladenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

  • CAS Number

    [889126-08-3]

  • Molecular Formula

    C11H14N8O3

  • Molecular Weight

    306.28

  • Smiles

    O[C@@H]1[C@H](N=[N+]=[N-])[C@@H](CO)O[C@H]1N(C=N2)C3=C2C(NC)=NC=N3

  • Target

    Nucleoside Antimetabolite/Analog

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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3’-Azido-3’-deoxy-N6-methyladenosine [CAS 889126-08-3]

3’-Azido-3’-deoxy-N6-methyladenosine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.