3-Cyanovinyl-9- (5’-O-DMT-2’-deoxyribofuranosyl) carbazole

3-Cyanovinyl-9- (5’-O-DMT-2’-deoxyribofuranosyl) carbazole is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

C41H36N2O5

636.73

O[C@H]1C[C@H](N2C(C=CC(/C=C/C#N)=C3)=C3C4=C2C=CC=C4)O[C@@H]1COC(C5=CC=CC=C5)(C6=CC=C(OC)C=C6)C7=CC=C(OC)C=C7

Nucleoside Antimetabolite/Analog

10 mM in DMSO

Room temperature