3-Deoxyglucosone [CAS 4084-27-9]

3-Deoxyglucosone (3-Deoxy-D-glucosone) is a reactive intermediate of the Maillard reaction and the polyol pathway. 3-Deoxyglucosone rapidly reacts with protein amino groups to form advanced glycation end products (AGEs), such as imidazolone, it is the most specific AGE for 3-DG. 3-Deoxyglucosone synergizes with low glucose to potentiate GLP-1 secretion and is considered as a biomarker for diabetes[1][2][3].

[4084-27-9]

C6H10O5

162.14

OC[C@@H](O)[C@@H](O)CC(C=O)=O

GLP Receptor

95

10 mM in DMSO

4°C (Powder, stored under nitrogen)

Room Temperature

H315, H319, H335

H315, H319, H335