3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles [CAS 287196-91-2]
3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles [CAS 287196-91-2]
SKU:QM-0147720-01
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Product Details
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Description
3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles is an inhibitor for bone morphogenetic protein 2 (BMP2) with an IC50 of 2.2 μM. 3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles is inhibitor for mitogen-activated protein kinase 1 (MEK1) . 3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles exhibits anti-inflammatory and neuroprotective activity in EAE mouse model[1][2].
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CAS Number
[287196-91-2]
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Molecular Formula
C11H6F3N3OS
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Molecular Weight
285.25
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Smiles
N#CC1=C(NC2=CC=CC=C2C(F)(F)F)SNC1=O
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Target
MEK; TGF-beta/Smad
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Purity
99.84
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Solubility
DMSO : 250 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles [CAS 287196-91-2]
3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.