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3-Hydroxy Midostaurin-d5
3-Hydroxy Midostaurin-d5
SKU:QM-0057929
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Product Details
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Description
3-Hydroxy Midostaurin-d5 is a deuterium labeled 3-Hydroxy Midostaurin. 3-Hydroxy Midostaurin is a metabolite of PKC412, which effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9.8 μM in culture medium and plasma, respectively[1].
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Molecular Formula
C35H25D5N4O5
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Molecular Weight
591.67
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Smiles
OC1NC(C2=C1C(C3=C4C=CC=C3)=C5N4[C@]6(O[C@@H](N7C5=C2C8=C7C=CC=C8)C[C@H]([C@H]6OC)N(C(C(C([2H])=C9[2H])=C(C([2H])=C9[2H])[2H])=O)C)C)=O
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Target
FLT3; Isotope-Labeled Compounds
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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3-Hydroxy Midostaurin-d5
3-Hydroxy Midostaurin-d5 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.