3-Methylcrotonyl CoA [CAS 6712-03-4]
3-Methylcrotonyl CoA [CAS 6712-03-4]
SKU:QM-0110418
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Product Details
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Description
3-Methylcrotonyl CoA is a key metabolic intermediate in the leucine degradation pathway, converted to 3-Methylglutaconyl CoA by 3-Methylcrotonyl CoA Carboxylase. Normally, 3-Methylglutaconyl CoA is catalyzed by 3-Methylglutaconyl-CoA Hydratase into 3-Hydroxy-3-methylglutaryl-CoA (HMG CoA) . However, mutations in 3-Methylglutaconyl-CoA Hydratase lead to the accumulation of 3-Methylglutaconyl CoA, causing metabolic disorders associated with 3MGA-uria. 3-Methylcrotonyl CoA is useful for research into metabolic diseases related to the leucine degradation pathway[1].
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CAS Number
[6712-03-4]
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Molecular Formula
C26H42N7O17P3S
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Molecular Weight
849.63
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Smiles
NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](OP(O)(O)=O)[C@@H](COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCSC(/C=C(C)\C)=O)=O)=O)(O)=O)(O)=O)O3
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Target
Drug Metabolite
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Shipping Conditions
Room temperature
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3-Methylcrotonyl CoA [CAS 6712-03-4]
3-Methylcrotonyl CoA is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.