3’-O- (2-Azidoethyl) adenosine
3’-O- (2-Azidoethyl) adenosine
SKU:QM-0070414
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Product Details
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Description
3’-O- (2-Azidoethyl) adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 3’-O- (2-Azidoethyl) adenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Molecular Formula
C12H16N8O4
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Molecular Weight
336.31
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Smiles
OC[C@@H]1[C@@H](OCCN=[N+]=[N-])[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N)O1
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Target
Nucleoside Antimetabolite/Analog
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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3’-O- (2-Azidoethyl) adenosine
3’-O- (2-Azidoethyl) adenosine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.