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3’-O- (2-Azidoethyl) adenosine

3’-O- (2-Azidoethyl) adenosine

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SKU:QM-0070414

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  • Description

    3’-O- (2-Azidoethyl) adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 3’-O- (2-Azidoethyl) adenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

  • Molecular Formula

    C12H16N8O4

  • Molecular Weight

    336.31

  • Smiles

    OC[C@@H]1[C@@H](OCCN=[N+]=[N-])[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N)O1

  • Target

    Nucleoside Antimetabolite/Analog

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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3’-O- (2-Azidoethyl) adenosine

3’-O- (2-Azidoethyl) adenosine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.