3’-O-MOE-A (Bz) -2’-CED-phosphoramidite [CAS 256224-01-8]

3’-O-MOE-A (Bz) -2’-CED-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[256224-01-8]

C50H58N7O9P

932.01

O=C(C1=CC=CC=C1)NC2=NC=NC3=C2N=CN3[C@H]4[C@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@H](OCCOC)[C@@H](COC(C5=CC=CC=C5)(C6=CC=C(OC)C=C6)C7=CC=C(OC)C=C7)O4

Nucleoside Antimetabolite/Analog

10 mM in DMSO

Room temperature