4′-DTMP [CAS 21253-58-7]

Name: 4′-DTMP [CAS 21253-58-7]
Brand: QuantiMol
SKU: QM-0196669-01
Price: 78.82 GBP
Availability: InStock

Size 25 mg 10 mM - 1 mL 50 mg

SKU:QM-0196669-01

£78.82 GBP

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Product Details

Description
4 '-DTMP is a DHFR inhibitor with Ki of 5.1 nM (DHFRWT) and 34.3 nM (DHFRL28R), respectively. 4 '-DTMP carries a polar modification that induces additional local interactions with the enzyme. In particular, the hairpin structure on the M20 ring is related to the internal communication of the DHFR. 4 '-DTMP has potential inhibition of E.coli[1].
CAS Number
[21253-58-7]
Molecular Formula
C13H16N4O3
Molecular Weight
276.3
Smiles
OC1=C(OC)C=C(CC2=CN=C(N)N=C2N)C=C1OC
Target
Dihydrofolate reductase (DHFR)
Concentration
10mM
Purity
97.85
Solubility
DMSO : 50 mg/mL (ultrasonic)
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping Conditions
Room Temperature
Hazard Statement
H302, H315, H319, H335
Precautions
H302, H315, H319, H335

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Variant	Variant total	Quantity	Price	Variant total
25 mgQM-0196669-01	25 mgQM-0196669-01 £78.82/ea	£0.00	Quantity	£78.82/ea	£0.00

10 mM - 1 mLQM-0196669-02	10 mM - 1 mLQM-0196669-02 £89.13/ea	£0.00	Quantity	£89.13/ea	£0.00

50 mgQM-0196669-03	50 mgQM-0196669-03 £118.38/ea	£0.00	Quantity	£118.38/ea	£0.00

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4′-DTMP is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.