4-Hydroxychalcone [CAS 20426-12-4]
4-Hydroxychalcone [CAS 20426-12-4]
SKU:QM-0112758-01
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Product Details
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Description
4-Hydroxychalcone is a chalcone metabolite with anti-angiogenic and anti-inflammatory activities. 4-Hydroxychalcone suppresses angiogenesis by suppression of growth factor pathway with no signs of cytotoxicity[1]. 4-Hydroxychalcone inhibits TNF-α induced NF-κB pathway activation and activates BMP signaling, reduces resistant hypertension (RH) by attenuating hyperaldosteronism and renal injury in mice[2].
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CAS Number
[20426-12-4]
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Molecular Formula
C15H12O2
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Molecular Weight
224.25
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Smiles
O=C(C1=CC=CC=C1)/C=C/C2=CC=C(O)C=C2
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Target
NF-κB
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Purity
99.29
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Solubility
DMSO : ≥ 250 mg/mL
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Storage Conditions
4°C (Powder, protect from light)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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4-Hydroxychalcone [CAS 20426-12-4]
4-Hydroxychalcone is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.