4'-Hydroxychalcone [CAS 2657-25-2]
4'-Hydroxychalcone [CAS 2657-25-2]
SKU:QM-0170949-01
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Product Details
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Description
4'-Hydroxychalcone is a chalcone isolated from licorice root, with hepatoprotective activity. 4'-Hydroxychalcone inhibits TNFα-induced NF-κB activation via proteasome inhibition. 4'-Hydroxychalcone induces a rapid potassium release from mitochondrial vesicles and causes deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria[1][2][3].
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CAS Number
[2657-25-2]
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Molecular Formula
C15H12O2
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Molecular Weight
224.25
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Smiles
O=C(C1=CC=C(O)C=C1)/C=C/C2=CC=CC=C2
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Target
Oxidative Phosphorylation; Proteasome
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Purity
99.66
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Solubility
DMSO : 233.33 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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4'-Hydroxychalcone [CAS 2657-25-2]
4'-Hydroxychalcone is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.