4-Hydroxyderricin [CAS 55912-03-3]
4-Hydroxyderricin [CAS 55912-03-3]
SKU:QM-0182925-01
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Product Details
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Description
4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is an orally active, potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3.43 μM. 4-Hydroxyderricin also mildly inhibits dopamine β (DBH) -hydroxylase activity. 4-Hydroxyderricin has antidepressant activity, anti-allergic, anti-diabetic, anti-oxidant, and antitumor effects. 4-Hydroxyderricin promotes apoptosis and cell cycle arrest through regulating PI3K/AKT/mTOR pathway in hepatocellular cells. 4-Hydroxyderricin inhibits osteoclast formation and accelerates osteoblast differentiation[1]. 4-Hydroxyderricin is promising for research of inflammatory diseases[1][2][3][4][5].
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CAS Number
[55912-03-3]
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Molecular Formula
C21H22O4
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Molecular Weight
338.4
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Smiles
O=C(C1=CC=C(OC)C(C/C=C(C)\C)=C1O)/C=C/C2=CC=C(O)C=C2
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Target
Apoptosis; Dopamine β-hydroxylase; Monoamine Oxidase
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Purity
99.94
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, protect from light)
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Shipping Conditions
Room Temperature
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4-Hydroxyderricin [CAS 55912-03-3]
4-Hydroxyderricin is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.