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4-Hydroxyestradiol [CAS 5976-61-4]
4-Hydroxyestradiol [CAS 5976-61-4]
SKU:QM-0113915-01
£339.17 GBP
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Product Details
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Description
4-Hydroxyestradiol (4-Hydroxy-17β-estradiol) is an endogenous metabolite of Estradiol. 4-Hydroxyestradiol is carcinogenic and shows mutagenic activity in breast epithelial cells. 4-Hydroxyestradiol inhibits the binding of Estradiol to the estrogen receptor in a competitive manner, with a Ki of 0.48 nM[1][2].
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CAS Number
[5976-61-4]
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Molecular Formula
C18H24O3
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Molecular Weight
288.38
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Smiles
C[C@@]12[C@](CC[C@@H]2O)([H])[C@@](CCC3=C4O)([H])[C@@](CC1)([H])C3=CC=C4O
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Target
Drug Metabolite; Endogenous Metabolite
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Purity
99
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Solubility
DMSO : 25 mg/mL (ultrasonic; warming)
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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4-Hydroxyestradiol [CAS 5976-61-4]
4-Hydroxyestradiol is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.