4-Hydroxynonenal [CAS 75899-68-2]
4-Hydroxynonenal [CAS 75899-68-2]
SKU:QM-0138119-01
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Product Details
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Description
4-Hydroxynonenal (4-HNE) is an α, β unsaturated hydroxyalkenal and an oxidative/nitrosative stress biomarker. 4-Hydroxynonenal is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2) . 4-Hydroxynonenal can modulate a number of signaling processes mainly through forming covalent adducts with nucleophilic functional groups in proteins, nucleic acids, and membrane lipids. 4-Hydroxynonenal plays an important role in cancer through mitochondria[1][2][3].
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CAS Number
[75899-68-2]
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Molecular Formula
C9H16O2
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Molecular Weight
156.22
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Smiles
CCCCCC(O)/C=C/C=O
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Target
Aldehyde Dehydrogenase (ALDH) ; Endogenous Metabolite
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Isoform
ALDH2; Human Endogenous Metabolite
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Purity
99.35
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
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Shipping Conditions
Blue Ice
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Hazard Statement
H225, H319
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Precautions
H225, H319
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4-Hydroxynonenal [CAS 75899-68-2]
4-Hydroxynonenal is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.